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AN300719L

Recombinant LRP6 Monoclonal Antibody

Größe

£221.40

War £246.00

SKU:
AN300719L
Zusätzliche Namen:
LRP,ADCAD,STHAG,LRP6,ADCAD2,STHAG7,C030016K15Rik,FLJ90062,FLJ90421,LDL receptor related protein 6,Low density lipoprotein receptor related protein 6,Low-density lipoprotein receptor-related protein 6,LRP-6,OTTHUMP00000238979,OTTHUMP00000238980,OTTHUMP00000238982
Anwendung:
WB
Konzentration:
0.2 mg/ml
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant Human LRP6 protein
Klon:
B658
Uniprot:
O75581
Synonyme:
ADCAD2;low-density lipoprotein receptor-related protein 6;LRP-6;STHAG7
Weitere Details:
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
Versandbedingungen:
Blue Ice