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AN300681L

Recombinant BMAL1 Monoclonal Antibody

Größe

£221.40

War £246.00

SKU:
AN300681L
Zusätzliche Namen:
JAP,MOP,MIC,Pgp,CDW,BMAL,PASD,CSPG,bHLHe,MDU,ARNTL,BMAL1,BMAL1c,JAP3,MOP3,PASD3,TIC,bHLHe5,aryl hydrocarbon receptor nuclear translocator like,IN,LHR,MC56,MDU2,MDU3,MIC4,Pgp1,CDW44,CSPG8,HCELL,HUTCH-I,ECMR-III,ARNT like protein 1 brain and muscle,Aryl hydrocarbon receptor nuclear translocator like protein 1,Aryl hydrocarbon receptor nuclear translocator-like protein 1,Basic helix loop helix PAS orphan MOP3,Basic helix loop helix PAS protein MOP3,Basic-helix-loop-helix-PAS protein MOP3,bHLH PAS
Anwendung:
WB
Konzentration:
0.2 mg/ml
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant Human BMAL1 protein
Klon:
B620
Uniprot:
O00327
Synonyme:
ARNT-like protein 1, brain and muscle;aryl hydrocarbon receptor nuclear translocator-like protein 1;basic helix-loop-helix family member e5;basic-helix-loop-helix-PAS orphan MOP3;basic-helix-loop-helix-PAS protein MOP3;bHLH-PAS protein JAP3;bHLHe5;BMAL1;BMAL1c;brain and muscle ARNT-like 1;class E basic helix-loop-helix protein 5;JAP3;member of PAS protein 3;member of PAS superfamily 3;MOP3;PAS domain containing 3;PAS domain-containing protein 3;PASD3;testis tissue sperm-binding protein Li 50e;TIC
Weitere Details:
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene.
Versandbedingungen:
Blue Ice