Recombinant CENP-A Monoclonal Antibody

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£221.40

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SKU:: AN300654L
Zusätzliche Namen:: CenH,CENPA,CENP-A,CenH3
Anwendung:: WB
Konzentration:: 0.2 mg/ml
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:: Recombinant Human CENP-A protein
Klon:: B589
Uniprot:: P49450
Synonyme:: CenH3;CENP-A;centromere autoantigen A;Centromere protein A;centromere protein A, 17kDa;centromere-specific histone;histone H3-like centromeric protein A
Weitere Details:: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms.