AN300581P
Recombinant TNF-alpha Monoclonal Antibody
Größe
£361.80
War £402.00
- SKU:
- AN300581P
- Zusätzliche Namen:
- MGC,Tnfsf,TNF-a,Cachectin,DIF,ICD1,ICD2,Membrane Form,MGC124630,N-terminal fragment,NTF,RATTNF,Soluble Form,TNF-alpha,Tumor Necrosis Factor,Tumor Necrosis Factor Ligand Superfamily Member 2,Tnf,Tnfa,Tnfsf2
- Anwendung:
- IF, ICC
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Rat
- Buffer:
- PBS
- Immunogen:
- Recombinant Rat TNF-alpha Protein
- Klon:
- B516
- Uniprot:
- P16599
- Synonyme:
- cachectin;RATTNF;TNF-alpha;Tnfa;tumor necrosis factor;tumor necrosis factor (TNF superfamily, member 2);tumor necrosis factor ligand superfamily member 2
- Weitere Details:
- TNF-A Alpha is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells. Many transformed cell lines also secrete TNF-A Alpha. Monomeric mouse TNF-A Alpha is 156 amino acid protein (N-glycosylated) with a reported molecular weight of 17.5 kD protein. TNF-A Alpha forms multimeric complexes, stable trimers are most common in solution. A 26 kD membrane form of TNF-A Alpha has also been described. TNF-A Alpha binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorraghic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils.
- Versandbedingungen:
- Blue Ice