AN300540P
Recombinant SLAMF8 Monoclonal Antibody
Größe
£361.80
War £402.00
- SKU:
- AN300540P
- Zusätzliche Namen:
- SLAM family member,SBBI,Slamf,B-lymphocyte activator macrophage expressed,CD353,SBBI42,SLAM family member 8,Blame,Slamf8,BLAME,SBBI42
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Mouse
- Buffer:
- PBS
- Immunogen:
- Recombinant Mouse SLAMF8 Protein
- Klon:
- B470
- Uniprot:
- Q9D3G2
- Synonyme:
- 5830408F06Rik;B lymphocyte activator macrophage expressed;B-lymphocyte activator macrophage expressed;Bla;Blame;SBBI;SBBI42;SLAM family member 8
- Weitere Details:
- The signaling lymphocyte activation molecule (SLAM) family includes homophilic and heterophilic receptors that modulate both adaptive and innate immune responses. These receptors share a common ectodomain organization: a membrane-proximal immunoglobulin constant domain and a membrane-distal immunoglobulin variable domain that is responsible for ligand recognition. SLAM family of receptors is expressed by a wide range of immune cells. Through their cytoplasmic domain, SLAM family receptors associate with SLAM-associated protein (SAP)-related molecules, a group of cytoplasmic adaptors composed almost exclusively of an SRC homology 2 domain. SLAM family receptors, in association with SAP family adaptors, have crucial roles during normal immune reactions in innate and adaptive immune cells. Mouse SLAM family member 8, also known as B-lymphocyte activator macrophage expressed, BCM-like membrane protein, SLAMF8 and BLAME, is a single-pass type I membrane protein. It contains one Ig-like C2-type (immunoglobulin-like) domain. SLAMF8/BLAME is expressed in lymph node, spleen, thymus and bone marrow. It may play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.
- Versandbedingungen:
- Blue Ice