AN300509P
Recombinant CD16/FCGR3 Monoclonal Antibody
Größe
£170.10
War £189.00
- SKU:
- AN300509P
- Zusätzliche Namen:
- CD-antigen,Fcgr,CD16,CD16 Protein,CD-antigen 16,Fc gamma Receptor III,FcRIII,IgG Fc receptor III,Low affinity immunoglobulin gamma Fc region receptor III,Mouse,Fcgr3
- Anwendung:
- WB, IP
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Mouse
- Buffer:
- PBS
- Immunogen:
- Recombinant Mouse CD16/FCGR3 protein
- Klon:
- B439
- Uniprot:
- P08508
- Synonyme:
- Fc-gamma RIII
- Weitere Details:
- Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcG GammaR). FcG GammaR is divided into three classes, Fc G Gamma RI (CD64), Fc G Gamma RII (CD32), and Fc G Gamma RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcG GammaRIIIa and CD16b/FcG GammaRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes.
- Versandbedingungen:
- Blue Ice