AN300476P
Recombinant CD27 Monoclonal Antibody
Größe
£361.80
War £402.00
- SKU:
- AN300476P
- Zusätzliche Namen:
- Tnfrsf,Tnfrsf7,Cd27,T14,S152,TNFRSF7,CD27 antigen,CD27L receptor,S152,T-cell activation antigen CD27,Tp55,Tumor necrosis factor receptor superfamily member 7
- Anwendung:
- Flow Cytometry, IF, ICC
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Mouse
- Buffer:
- PBS
- Immunogen:
- Recombinant Mouse CD27 protein
- Klon:
- B406
- Uniprot:
- P41272
- Synonyme:
- CD antigen 27;CD27 antigen;CD27L receptor;S15;S152;T-cell activation antigen CD27;Tnfr;Tnfrsf7;Tp5;Tp55;tumor necrosis factor receptor superfamily member 7
- Weitere Details:
- CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has an important role in the generation of T cell immunity and is an robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.
- Versandbedingungen:
- Blue Ice