AN300453P
Recombinant PDHA1 Monoclonal Antibody
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£311.40
War £346.00
- SKU:
- AN300453P
- Zusätzliche Namen:
- PDHA1,PDHA,PDHAD,PDHCE1A,PHE1A,E1 alpha polypeptide 1,mitochondrial,ODPA,PDH,PDHE1 A type I,PDHE1-A type I,PDHA Alpha,Pyruvate Dehydrogenase (lipoamide) alpha 1,Pyruvate dehydrogenase complex,Pyruvate Dehydrogenase E1 alpha,Pyruvate dehydrogenase E1 component subunit alpha,somatic form
- Anwendung:
- IF, ICC
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human PDHA1 Protein
- Klon:
- B379
- Uniprot:
- P08559
- Synonyme:
- PDHA;PDHAD;PDHCE1A;PDHE1-A type I;PHE1A;pyruvate dehydrogenase (lipoamide) alpha 1;pyruvate dehydrogenase alpha 1;pyruvate dehydrogenase complex, E1-alpha polypeptide 1;pyruvate dehydrogenase E1 alpha 1 subunit;pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
- Weitere Details:
- The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice