Recombinant Gastric intrinsic factor/GIF Monoclonal Antibody

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£361.80

War £402.00

SKU:: AN300441P
Zusätzliche Namen:: TCN,IF,INF,TCN3,Transcobalamin III,Vitamin B Synthesis,GIF,IFMH,CBLIF
Anwendung:: WB, IP
Konzentration:: 1 mg/ml
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS
Immunogen:: Recombinant Human Gastric intrinsic factor/GIF Protein
Klon:: B367
Uniprot:: P27352
Synonyme:: cobalamin binding intrinsic factor;gastric intrinsic factor (vitamin B synthesis);GIF;IF;IFMH;INF;intrinsic factor;TCN3
Weitere Details:: Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the absorption of vitamin B12 on in the small intestine. Vitamin B12 bounds to haptocorrin after entry into the stomach. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to gastric intrinsic factor. This new complex travels to the ileum, where special epithelial cells endocytose them. Inside the cell, B12 dissociates once again and binds to another protein, transcobalamin II. The new complex can exit the epithelial cells to enter the liver.