AN300412P
Recombinant alpha-Galactosidase A/GLA Monoclonal Antibody
Größe
£170.10
War £189.00
- SKU:
- AN300412P
- Zusätzliche Namen:
- GLA,GALA,Alpha-D-Galactoside,Galactohydrolase,galactosidase alpha,GLAL,Melibiase,Agalsidase,Alpha-galactosidase A,Alpha-D-galactosidase A,Alpha-D-galactoside galactohydrolase,Galactosylgalactosylglucosylceramidase GLA
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human alpha-Galactosidase A/GLA protein
- Klon:
- B338
- Uniprot:
- P06280
- Synonyme:
- agalsidase alfa;alpha-D-galactosidase A;Alpha-D-galactoside galactohydrolase;alpha-D-galactoside galactohydrolase 1;alpha-gal A;alpha-galactosidase A;GALA;galactosylgalactosylglucosylceramidase GLA;melibiase
- Weitere Details:
- alpha -Galactosidase A is a homodimeric glycoprotein that can release terminal alpha -galactosyl moieties from glycolipids and glycoproteins and catalyze the hydrolysis of melibiose into galactose and glucose . It is a lysosomal enzyme and is responsible for degradation of glycolipid globotriaosylceramide (Gb3) (Gal alpha 1-4Gal beta 1-4Glc beta -ceramide). Mutations in this gene cause Fabry disease, an X-linked hereditary lysosomal storage disease with the accumulation of Gb3 in the walls of small blood vessels, nerves, dorsal root ganglia, renal glomerular and tubular epithelial cells, and cardiomyocytes .
- Versandbedingungen:
- Blue Ice