Recombinant MESDC2 Monoclonal Antibody

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£361.80

War £402.00

SKU:: AN300356P
Zusätzliche Namen:: UNQ,PRO,KIAA,MESDC,MESDC2,BOCA,MESD,KIAA0081,MESDM,UNQ1911,PRO4369
Anwendung:: WB, IF, ICC, IP
Konzentration:: 1 mg/ml
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS
Immunogen:: Recombinant Human MESDC2 protein
Klon:: B278
Uniprot:: Q14696
Synonyme:: BOCA;LDLR chaperone MESD;LRP chaperone MESD;MESDC2;mesoderm development candidate 2;mesoderm development LRP chaperone MESD;mesoderm development protein;OI20;renal carcinoma antigen NY-REN-61
Weitere Details:: Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs. Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ formation by promoting cell-surface expression of LRP4 (By similarity. May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE cells (By similarity.