Recombinant Ano1 Monoclonal Antibody

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£361.80

War £402.00

SKU:: AN300309P
Zusätzliche Namen:: ANO,DOG,TAOS,ORAOV,ANO1,DOG1,ORAOV2,TAOS2,TMEM16A
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS
Immunogen:: A synthetic peptide corresponding to the C-terminus of the Human Ano1
Klon:: B231
Uniprot:: Q5XXA6
Synonyme:: anoctamin 1, calcium activated chloride channel;anoctamin-1;Ca2+-activated Cl- channel;calcium activated chloride channel;discovered on gastrointestinal stromal tumors protein 1;DOG1;oral cancer overexpressed 2;Oral cancer overexpressed protein 2;ORAOV2;TAOS2;TMEM16A;Transmembrane protein 16A;transmembrane protein 16A (eight membrane-spanning domains);tumor-amplified and overexpressed sequence 2
Weitere Details:: Calcium-activated chloride channel (CaCC which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.