AN300241P
Recombinant CALML5 Monoclonal Antibody
Größe
£361.80
War £402.00
- SKU:
- AN300241P
- Zusätzliche Namen:
- Calmodulin like,Calmodulin-like protein,CALML,CALL5_HUMAN,Calmodulin like 5,Calmodulin-like protein 5,Calmodulin-like skin protein,CLSP,CALML5
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human CALML5 protein
- Klon:
- B159
- Uniprot:
- Q9NZT1
- Synonyme:
- calmodulin-like protein 5;calmodulin-like skin protein;CLSP
- Weitere Details:
- Calmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains fourEF-hand domains. CALML5/CLSP is particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation.The expression is very low in lung. CALML5/CLSP binds calcium. It may be involved in terminal differentiation of keratinocytes. Coxsackievirus and adenovirus receptor (CAR) is a member of the immunoglobulin (Ig) superfamily and a component of epithelial tight junction. CAR functions as a primary receptor for coxsackievirus B and adenovirus (Ad) infection. CALML5/CLSP is closely related to CAR. The structure and dynamics of human calmodulin-like skin protein CALML5/CLSP have been characterized by NMR spectroscopy. The mobility of CALML5/CLSP has been found to be different for the N-terminal and C-terminal domains. The N-terminal domain is characterized by four stable helices, which experience large fluctuations. This is shown to be due to mutations in the hydrophobic core. The overall N-terminal domain behavior is similar both in the full-length protein and in the isolated domain.
- Versandbedingungen:
- Blue Ice