AN300166P
Recombinant CD302/CLEC13A Monoclonal Antibody
Größe
£361.80
War £402.00
- SKU:
- AN300166P
- Zusätzliche Namen:
- 1110055L24Rik,AI159627,Clec13a,Cd302,DCL1
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Mouse
- Buffer:
- PBS
- Immunogen:
- Recombinant Mouse CD302 / CLEC13A protein
- Klon:
- A1280
- Uniprot:
- Q9DCG2
- Synonyme:
- 1110055L24Rik;AI159627;C-type lectin domain family 13 member A;CD302 antigen;type I transmembrane C-type lectin receptor DCL-1
- Weitere Details:
- CD302/CLEC13A (C-type lectin domain family 13 member A), also known as C-type lectin receptor DCL-1, is a type I transmembrane C-type lectin DCL-1/CD302. DCL-1 protein was highly conserved among the human, mouse, and rat orthologs. DCL-1 ectodomain contains only one CRD, whereas other type I transmembrane C-type lectins contain more than one domain (e.g. selectins and MMR). DCL-1 CP contains several putative motifs, including a Tyr-based internalization, a cluster of acidic amino acids, and Ser and Tyr phosphorylation motifs, suggesting that DCL-1 CP mediates not only endocytosis and late endosome targeting but also signaling. DCL-1 may be another cell/matrix adhesion receptor integrated in cell adhesion complexes and that DCL-1 dysfunction may affect APC adhesion and migration, causing suppression of APC function.
- Versandbedingungen:
- Blue Ice