AN300092P
Recombinant 2B4/CD244 Monoclonal Antibody
Größe
£170.10
War £189.00
- SKU:
- AN300092P
- Zusätzliche Namen:
- h2B,SLAM family member,Natural killer cell receptor 2B,NKR2B,SLAMF,CD244,2B4,NAIL,NKR2B4,Nmrk,SLAMF4,h2B4,Natural killer cell receptor 2B4,NK cell activation-inducing ligand,SLAM family member 4,2B4,C9.1,CD244 antigen,CD244 molecule,CD244 molecule natural killer cell receptor 2B4,CD244 natural killer cell receptor 2B4,F730046O15Rik,Ly90,member 4,Natural killer cell activation-inducing ligand,NK cell activation inducing ligand,NK cell activation inducing ligand NAIL,NK cell type I receptor
- Anwendung:
- WB, IP
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human 2B4 / CD244 protein
- Klon:
- A1206
- Uniprot:
- Q9BZW8
- Synonyme:
- 2B4;CD244 molecule, natural killer cell receptor 2B4;h2B4;NAIL;natural killer cell receptor 2B4;NK cell activation inducing ligand NAIL;NK cell activation-inducing ligand;NK cell type I receptor protein 2B4;NKR2B4;Nmrk;signaling lymphocytic activation molecule 4;SLAM family member 4;SLAMF4
- Weitere Details:
- CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including most CD8+ T cells and G Gamma/D Delta T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression.
- Versandbedingungen:
- Blue Ice