AN300079P
Recombinant LIFR/CD118 Monoclonal Antibody
Größe
£361.80
War £402.00
- SKU:
- AN300079P
- Zusätzliche Namen:
- SJS,LIFR,CD118,LIF-R,SJS2,STWS,SWS,gp190
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human LIFR protein
- Klon:
- A1189
- Uniprot:
- P42702
- Synonyme:
- CD118;CD118 antigen;leukemia inhibitory factor receptor;leukemia inhibitory factor receptor alpha;LIF receptor alpha;LIF-R;SJS2;STWS;SWS
- Weitere Details:
- This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5,8)(p13,q12) with the pleiomorphic adenoma gene 2, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene.
- Versandbedingungen:
- Blue Ice