AN300052P
Recombinant Insulin Monoclonal Antibody
Größe
£311.40
War £346.00
- SKU:
- AN300052P
- Zusätzliche Namen:
- MODY,IDDM,IDDM1,IDDM2,ILPR,IRDN,MODY10,INS,Insulin,Connecting Peptide,Insulin A chain,Insulin B chain,Preproinsulin,Proinsulin,Proinsulin precursor,IDDM,IDDM1,IDDM2,ILPR,ins,INS,Insulin A chain,Insulin B chain,IRDN,MODY10,Preproinsulin,Proinsulin,Proinsulin precursor,Pro-Insulin
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human Insulin Protein
- Klon:
- A1162
- Uniprot:
- P01308
- Synonyme:
- IDDM;IDDM1;IDDM2;ILPR;insulin;IRDN;MODY10;PNDM4;preproinsulin;proinsulin
- Weitere Details:
- After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice