AN300033P
Recombinant Caspase-14/CASP14 Monoclonal Antibody
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£361.80
War £402.00
- SKU:
- AN300033P
- Zusätzliche Namen:
- ARCI,Caspase,CASP14,ARCI12,CASP-14,Caspase-14,MGC119078,MGC119079
- Anwendung:
- IHC-P, IF, ICC
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human Caspase-14 / CASP14 protein
- Klon:
- A1143
- Uniprot:
- P31944
- Synonyme:
- apoptosis-related cysteine protease;ARCI12;CASP-14;caspase 14, apoptosis-related cysteine peptidase;caspase 14, apoptosis-related cysteine protease;caspase-14
- Weitere Details:
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 7 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
- Versandbedingungen:
- Blue Ice