AN300004P
Recombinant HER2/ErbB2/CD340 Monoclonal Antibody
Größe
£170.10
War £189.00
- SKU:
- AN300004P
- Zusätzliche Namen:
- TKR,ERBB,erb-b2 receptor tyrosine kinase,Receptor tyrosine-protein kinase erbB,Tyrosine kinase-type cell surface receptor HER,HER2/ErbB,HER,MLN,ERBB2,CD340,HER-2,HER-2/neu,HER2,MLN 19,NEU,NGL,TKR1,erb-b2 receptor tyrosine kinase 2,HER2/ErbB2,MLN19,Metastatic lymph node gene 19 protein,p185,Proto-oncogene Neu,Receptor tyrosine-protein kinase erbB-2,Tyrosine kinase-type cell surface receptor HER2,Neu,erb-B2,CD340,erb-b2 receptor tyrosine kinase 2,HER2,HER-2,HER-2/neu,MLN 19,MLN19,NGL,TKR1,C erb
- Anwendung:
- Flow Cytometry, IHC-P, IF, ICC
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human HER2/ErbB2/CD340 Protein
- Klon:
- A1114
- Uniprot:
- P04626
- Synonyme:
- c-erb B2/neu protein;CD340;HER-2;HER-2/neu;HER2;herstatin;human epidermal growth factor receptor 2;metastatic lymph node gene 19 protein;MLN 19;NEU;neuro/glioblastoma derived oncogene homolog;neuroblastoma/glioblastoma derived oncogene homolog;NGL;p185erbB2;proto-oncogene c-ErbB-2;proto-oncogene Neu;receptor tyrosine-protein kinase erbB-2;TKR1;tyrosine kinase-type cell surface receptor HER2;v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2;v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2;v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog;VSCN2
- Weitere Details:
- ErbB2, also called Neu and Her2, is a transmembrane glycoprotein in the ErbB family of tyrosine kinase receptors for EGF superfamily growth factors. ErbB2 is widely expressed in epithelial cells and over-expressed in a large number of breast carcinomas. ErbB2 has no identified ligands but heterodimerizes with ErbB1/EGF R, ErbB3, or ErbB4 to form higher affinity signaling complexes. The protease ADAM10 releases a 110 kDa soluble fragment of ErbB2 from the cell surface. ErbB2 plays roles in development, cancer, communication at the neuromuscular junction, and regulation of cell growth and differentiation. The ErbB2/ErbB3 heterodimer is expressed in the majority of breast, skin, ovary and gastrointestinal tumors and transduces a highly mitogenic signal in response to neuregulin 1 (NRG1, heuregulin 1) or NRG2. ErbB3, ErbB2 and neuregulin are all required for formation of the sympathetic nervous system.
- Versandbedingungen:
- Blue Ice