AN200229P
VISTA/GI24/B7-H5 Monoclonal Antibody
Größe
£311.40
War £346.00
- SKU:
- AN200229P
- Zusätzliche Namen:
- UNQ,PRO,Platelet receptor Gi,Stress-induced secreted protein,C10orf,Platelet receptor Gi24,Sisp-1,Stress-induced secreted protein-1,C10orf54,SISP1,VISTA,VSIR,PP2135,UNQ730,PRO1412,B7H5,B7-H5,DD1alpha,GI24,PD-1H
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human VISTA/GI24/B7-H5 Protein
- Klon:
- A1081
- Uniprot:
- Q9H7M9
- Synonyme:
- B7-H5;B7H5;C10orf54;DD1alpha;Death Domain1alpha;Dies1;GI24;PD-1H;PDCD1 homolog;platelet receptor GI24;PP2135;sisp-1;SISP1;stress-induced secreted protein-1;V-domain Ig suppressor of T cell activation;V-set domain-containing immunoregulatory receptor;V-set immunoregulatory receptor;V-type immunoglobulin domain-containing suppressor of T-cell activation;VISTA
- Weitere Details:
- VSIR (V-Set Immunoregulatory Receptor, also known as VISTA) is a Protein Coding gene. VISTA is an immunoregulatory receptor that inhibits the T-cell response. It may promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. VSIR, or V-set immunoregulatory receptor, could be involved in the pathogenesis of chronic rhinosinusitis with nasal polyps. V-domain Immunoglobulin Suppressor of T cell Activation (VISTA) is an inhibitory immune-checkpoint molecule that suppresses CD4+ and CD8+ T cell activation when expressed on antigen-presenting cells. VSIR is broadly expressed in the spleen, bone marrow, and other tissues. Diseases associated with VSIR include Ichthyosis, Congenital, Autosomal Recessive 6, and Monckeberg Arteriosclerosis. An important paralog of this gene is VSIG8.
- Versandbedingungen:
- Blue Ice