AN200175P
CD16a/FCGR3A Monoclonal Antibody
Größe
£311.40
War £346.00
- SKU:
- AN200175P
- Zusätzliche Namen:
- FCR,IMD,FCG,Fcgr,IGFR,IgG Fc Receptor III,CD16,CD16A,FCG3,FCGR3,FCGRIII,FCR-10,FCRIII,FCRIIIA,IGFR3,IMD20,FCGR3A,CD16a Antigen,Fc-Gamma RIII,Fc-gamma RIIIa,Fc-Gamma RIII-Alpha,IgG Fc Receptor III-2,Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A,Fc&,gamma-RIIIA-A,CD16a,CD 16,CD 16a,CD16B,CD16b antigen,Fc fragment of IgG,Fc fragment of IgG low affinity IIIa receptor,Fc fragment of IgG low affinity IIIa receptor (CD16),Fc fragment of IgG receptor IIIa,Fc gamma R3,Fc gamma receptor
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human CD16a/FCGR3A protein
- Klon:
- A1027
- Uniprot:
- P08637
- Synonyme:
- CD16;CD16A;CD16a antigen;Fc fragment of IgG, low affinity III, receptor for (CD16);Fc fragment of IgG, low affinity IIIa, receptor (CD16a);Fc gamma receptor III-A;Fc-gamma receptor III-2 (CD 16);Fc-gamma receptor IIIb (CD16);Fc-gamma RIII-alpha;FCG3;FcgammaRIIIA;FCGR3;FCGRIII;FCR-10;FCRIII;FCRIIIA;IGFR3;igG Fc receptor III-2;IMD20;immunoglobulin G Fc receptor III;low affinity immunoglobulin gamma Fc region receptor III-A;low affinity immunoglobulin gamma receptor III-a Fc fragment;neutrophil-specific antigen NA
- Weitere Details:
- This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice