AN200069P
TXNRD1 Monoclonal Antibody
Größe
£311.40
War £346.00
- SKU:
- AN200069P
- Zusätzliche Namen:
- TRXR,TXNRD,TXNRD1,GRIM-12,TR,TR1,TRXR1,TXNR,GRIM12,KDRF
- Anwendung:
- Flow Cytometry, IF, ICC
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human TXNRD1 protein
- Klon:
- A917
- Uniprot:
- Q16881
- Synonyme:
- gene associated with retinoic and IFN-induced mortality 12 protein;gene associated with retinoic and interferon-induced mortality 12 protein;GRIM-12;KM-102-derived reductase-like factor;oxidoreductase;selenoprotein TXNRD1;testis tissue sperm-binding protein Li 46a;thioredoxin reductase 1, cytoplasmic;thioredoxin reductase GRIM-12;thioredoxin reductase TR1;TR;TR1;TRXR1;TXNR
- Weitere Details:
- This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 0&apos, UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
- Versandbedingungen:
- Blue Ice