AN200057P
Adenosine Deaminase Monoclonal Antibody
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£311.40
War £346.00
- SKU:
- AN200057P
- Zusätzliche Namen:
- ADA,adenosine deaminase,adenine deaminase,Adenosine Aminhydrolase,EC 3.5.4.4,ADA1,Adenosine aminohydrolase
- Anwendung:
- WB, IP
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human Adenosine Deaminase Protein
- Klon:
- A905
- Uniprot:
- P00813
- Synonyme:
- ADA1;adenosine aminohydrolase;adenosine deaminase
- Weitere Details:
- Adenosine Deaminase (ADA, adenosine aminohydrolase) is one of the key enzymes of purine nucleotide catabolism. It catalyses the hydrolytic deamination of adenosine and deoxy-adenosine to inosine and deoxyinosine . ADA is expressed in virtually all tissues and is expressed at high levels in T-lymphocytes. Adenosine Deaminase deficiency can cause a form of SCID (severe combined immunodeficiency) and lymphopenia in both B- and T-cell lineages . ADA can be used as a sensitive diagnostic marker for tuberculous pleuritis . Although it is primarily a cytosolic enzyme, ADA is known to be a positive regulator of T-cell co-activation due to its binding to CD26 at the cell surface. The interaction of ADA with CD26 regulates lymphocyte-epithelial cell adhesion
- Versandbedingungen:
- Blue Ice