AN200006P
CD63 Monoclonal Antibody
Größe
£311.40
War £346.00
- SKU:
- AN200006P
- Zusätzliche Namen:
- MLA,LAMP,Tetraspanin,CD antigen CD,Melanoma-associated antigen ME,Lysosomal-associated membrane protein,CD63,LAMP-3,ME491,MLA1,OMA81H,TSPAN30,CD63 antigen,CD antigen CD63,CD63 molecule,Granulophysin,Lysosomal-associated membrane protein 3,Melanoma-associated antigen ME491,Ocular melanoma-associated antigen,Tetraspanin-30,Tspan-30,LIMP,MLA1,LAMP-3,CD 63,CD63 antigen (melanoma 1 antigen),CD63 antigen melanoma 1 antigen,gp55,LAMP 3,LAMP3,Lysosomal associated membrane protein 3,Lysosome associated
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS
- Immunogen:
- Recombinant Human CD63 protein
- Klon:
- A850
- Uniprot:
- P08962
- Synonyme:
- CD63 antigen;CD63 antigen (melanoma 1 antigen);granulophysin;LAMP-3;lysosomal-associated membrane protein 3;lysosome-associated membrane glycoprotein 3;ME491;melanoma-associated antigen ME491;melanoma-associated antigen MLA1;MLA1;ocular melanoma-associated antigen;OMA81H;tetraspanin-30;tspan-30;TSPAN30
- Weitere Details:
- Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
- Versandbedingungen:
- Blue Ice