AN100004P
PAK1 Antibody Polyclonal Antibody
Größe
£311.40
War £346.00
- SKU:
- AN100004P
- Zusätzliche Namen:
- PAK,Pak1
- Anwendung:
- WB, IF, ICC, IP
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Rat
- Buffer:
- PBS
- Immunogen:
- A synthetic peptide corresponding to the C-terminus of the Rat PAK1
- Uniprot:
- P35465
- Synonyme:
- alpha-PAK;p21 (CDKN1A)-activated kinase 1;p21 protein (Cdc42/Rac)-activated kinase 1;p21-activated kinase 1;p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related);p68-PAK;PAK-1;protein kinase MUK2;serine/threonine-protein kinase PAK 1
- Weitere Details:
- P21-activated kinase-1 (PAK1) is an enzyme associated with multiple metabolic networks and different types of cancers.PAK1 (RAC/CDC42-activated kinase 1) is the major oncogenic/ageing kinase, and its dysfunction extends the healthy lifespan of C. elegans by activating HSP16 gene. The p21 protein (Cdc42/Rac)-activated kinase 1 (PAK1) expression appears to be predictive of prognosis in various solid tumors. PAK1 expression may be a predictive marker of overall survival and disease-specific survival in patients with solid tumors.p21-Activated kinase 1 (PAK1) has attracted much attention as a potential therapeutic target due to its central role in many oncogenic signaling pathways, its frequent dysregulation in cancers and neurological disorders, and its tractability as a target for small-molecule inhibition.
- Versandbedingungen:
- Blue Ice