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  2. Polyclonal

AN006750L

S100A1 Polyclonal Antibody

Größe

£120.60

War £134.00

SKU:
AN006750L
Zusätzliche Namen:
S100A,S100A1,Bpb,NEF,Protein S100-A1,S100,S100 alpha,S100 beta,S100 calcium binding protein A1,S100 calcium binding protein B,S100 calcium-binding protein A1,S-100 protein alpha chain,S100 protein alpha polypeptide,S-100 protein subunit alpha,S100-alpha,S100B,S100beta,S100A1
Anwendung:
WB
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Mouse
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:
Recombinant Human S100A1 protein expressed by E.coli
Uniprot:
P23297
Synonyme:
protein S100-A1;S-100 protein alpha chain;S-100 protein subunit alpha;S100;S100 alpha;S100 calcium-binding protein A1;S100 protein, alpha polypeptide;S100-alpha;S100A
Weitere Details:
Small calcium binding protein that plays important roles in several biological processes such as Ca2+ homeostasis, chondrocyte biology and cardiomyocyte regulation. In response to an increase in intracellular Ca2+ levels, binds calcium which triggers conformational changes .These changes allow interactions with specific target proteins and modulate their activity.Regulates a network in cardiomyocytes controlling sarcoplasmic reticulum Ca2+ cycling and mitochondrial function through interaction with the ryanodine receptors RYR1 and RYR2, sarcoplasmic reticulum Ca2+-ATPase/ATP2A2 and mitochondrial F1-ATPase. Facilitates diastolic Ca2+ dissociation and myofilament mechanics in order to improve relaxation during diastole.
Versandbedingungen:
Blue Ice