ANGPTL4 Polyclonal antibody

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£120.60

War £134.00

SKU:: AN006110L
Zusätzliche Namen:: ARP,Secreted protein Bk,Angiopoietin-like protein,Angiopoietin-related protein,ANGPTL,425O18,425O18-1,Angiopoietin-like protein 4,Angiopoietin-related protein 4,ARP4,Fasting-induced adipose factor,Hepatic fibrinogen/angiopoietin-related protein,HFARP,NL2,PGAR,pp1158,Secreted protein Bk89,Farp,Fiaf,Ng27,Angptl4
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:: Recombinant Mouse ANGPTL4 protein expressed by Mammalian
Uniprot:: Q9Z1P8
Synonyme:: 425O18-1;angiopoietin-like protein 4;angiopoietin-related protein 4;Arp4;Bk89;fasting-induced adipose factor;FI;Fiaf;fibrinogen/angiopoietin-related protein;hepatic fibrinogen/angiopoietin-related protein;HF;Hfarp;major histocompatibility complex region NG27;NG2;Ng27;Pgar;Pgarg;Pp1158;secreted protein Bk89
Weitere Details:: Angiopoietin-related protein 4 (ANGPTL4) is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

Versandbedingungen:: Blue Ice