PE Anti-Human CD11a Antibody[38]

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£99.90

War £111.00

SKU:: AN00569D
Zusätzliche Namen:: LFA-1A Alpha chain,Integrin A AlphaL subunit,A AlphaL Integrin,ITGAL
Anwendung:: Flow Cytometry
Lagerbedingungen:: 2-8[o]C Do not freeze. Protect from light.
Hersteller:: Elabscience
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS
Immunogen:: CD11a
Klon:: 38
Uniprot:: P20701
Synonyme:: antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide;CD11 antigen-like family member A;CD11A;integrin alpha-L;integrin gene promoter;integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide);leukocyte adhesion glycoprotein LFA-1 alpha chain;leukocyte function-associated molecule 1 alpha chain;LFA-1;LFA-1 alpha;LFA-1A;LFA1A;lymphocyte function-associated antigen 1, alpha polypeptide
Weitere Details:: CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1A Alpha chain and integrin A AlphaL subunit. CD11a non-covalently associates with integrin B Beta2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).