AN00568D
PE Anti-Human TCR VA Alpha24-JA Alpha18 Antibody[6B11]
Größe
£111.60
War £124.00
- SKU:
- AN00568D
- Zusätzliche Namen:
- TCR VA Alpha24-JA Alpha18,TCR VA Alpha24-JA AlphaQ,invariant NKT cell,iNKT
- Anwendung:
- Flow Cytometry
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS
- Immunogen:
- TCR Vα24-Jα18
- Klon:
- 6B11
- Synonyme:
- TCRAV18S1;TCRAV24S1
- Weitere Details:
- Encoded by the TCR VA Alpha24-JA Alpha18 germline configuration, VA Alpha24-JA AlphaQ is expressed on a subset of NKT cells, namely invariant NKT (iNKT). VA Alpha24-JA AlphaQ TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production. iNKT cells have been implicated in immune regulation, tumor surveillance, and host response to pathogens. While iNKT cells occur at low frequency in the blood, assorted chemokines contribute to their tissue homing potential.
- Versandbedingungen:
- Blue Ice