APC Anti-Mouse LPAM-1 Antibody[DATK32]

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SKU:: AN00563E
Zusätzliche Namen:: A Alpha4B Beta7 Integrin,CD49d/B Beta7,LPAM-1,ITGA4,ITGB7
Anwendung:: Flow Cytometry
Lagerbedingungen:: 2-8[o]C Do not freeze. Protect from light.
Hersteller:: Elabscience
Host:: Rat
Reaktivitäten:: Mouse
Buffer:: PBS
Immunogen:: LPAM-1
Klon:: DATK32
Uniprot:: P26011, Q00651
Synonyme:: CD49 antigen-like family member D;CD49D;integrin alpha-4;integrin alpha-IV;integrin alpha4B;integrin beta-7;integrin beta-P;Itga4B;LPAM subunit alpha;Ly69;lymphocyte Peyer patch adhesion molecules subunit alpha;M290 IEL antigen;VLA-4 receptor, alpha 4 subunit;VLA-4 subunit alpha
Weitere Details:: DATK32 antibody is specific for a combinatorial determinate of integrin A Alpha4B Beta7complex. Integrin A Alpha4B Beta7 is composed of a 150 kD (A Alpha4 or CD49d) and a 130 kD (B Beta7) heterodimer, also known as CD49d/B Beta7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors). Integrin A Alpha4B Beta7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues.