AN00428E
APC Anti-Mouse CD45R (B220) Antibody[RA3-6B2]
Größe
£72.90
War £81.00
- SKU:
- AN00428E
- Zusätzliche Namen:
- CD45R,B220
- Anwendung:
- Flow Cytometry
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Host:
- Rat
- Reaktivitäten:
- Mouse
- Buffer:
- PBS
- Immunogen:
- CD45R/B220
- Klon:
- RA3-6B2
- Uniprot:
- Q64224
- Weitere Details:
- CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker. CD19, however, may be more appropriate for B cell specificity.
- Versandbedingungen:
- Blue Ice