APC Anti-Human CD55 Antibody[HI55a]

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£115.20

War £128.00

SKU:: AN00336E
Zusätzliche Namen:: Complement decay-accelerating factor,CD55,CR,DAF
Anwendung:: Flow Cytometry
Lagerbedingungen:: 2-8[o]C Do not freeze. Protect from light.
Hersteller:: Elabscience
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS
Immunogen:: CD55
Klon:: HI55a
Uniprot:: P13591
Synonyme:: antigen recognized by monoclonal antibody 5.1H11;CD55 antigen;CD55 molecule, decay accelerating factor for complement (Cromer blood group);CD56;CHAPLE;complement decay-accelerating factor;CR;CROM;Cromer blood group antigen;DAF;MSK39;NCAM;neural cell adhesion molecule 1;neural cell adhesion molecule, NCAM;Rh blood group D antigen;TC
Weitere Details:: CD55 is a 60-70 kD glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein also known as decay-accelerating factor (DAF). It is expressed on hematopoietic cells including erythrocytes and many non-hematopoietic cells. CD55 accelerates the dissociation of the components of the C3-convertases (namely C2a from C4b in the C4bC2a complex, a C3-convertase of the classical pathway, and factor Bb from the C3bBb complex, a C3-convertase of the alternative pathway) to protect cells from inappropriate damage caused by autologous complement. CD55 has been reported to reduce the efficiency of NK cell lysis and induce signal transduction in T cells. CD55 has also been shown to interact with CD97 and bind to Coxsackie and Echovirus.