Y07001H
Recombinant Human PDGF-AA
Größe
£457.00
- SKU:
- Y07001H
- Zusätzliche Namen:
- Platelet-Derived Growth Factor-AA，PDGF-A, PDGF1
- Anwendung:
- Functional Assay
- Molekulargewicht:
- 14.3 kDa
- Reinheit:
- ≥95% by SDS-PAGE
- Lagerbedingungen:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Hersteller:
- East-Mab Biomedical
- Host:
- Hamster
- ABP:
- No Import Docs
- Formulierung:
- Lyophilized from a 0.22 um filtered solution containing PBS, 5% mannitol and 0.01% Tween 80, pH7.4
- Format:
- Lyophilized powder
- Weitere Details:
- PDGF-AA (Platelet-Derived Growth Factor-AA), a subtype of the platelet-derived growth factor (PDGF) family, consists of two identical A chains. It primarily regulates cellular processes such as proliferation, migration, differentiation, and survival by activating tyrosine kinase receptors on the cell membrane (PDGFR-αα, PDGFR-αβ, or PDGFR-ββ). PDGF-AA specifically binds to the PDGFR-αα receptor and stimulates the proliferation of specific cell types, including fibroblasts, glial cells, and mesenchymal stem cells (MSCs), making it widely used for expanding primary or hard-to-culture cells. In wound healing and tissue engineering research, PDGF-AA can induce directed cell migration to mimic in vivo repair processes. For certain mesenchymal stem cells or neural precursor cells, it helps maintain their undifferentiated state or promotes directed differentiation—such as toward osteogenic or glial lineages.
- Versandbedingungen:
- Blue Ice