Y06941H
Recombinant Human β-NGF
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£363.00
- SKU:
- Y06941H
- Zusätzliche Namen:
- Beta‑Nerve Growth Factor，β-NGF，NGFB
- Anwendung:
- Functional Assay
- Molekulargewicht:
- 13.4 kDa
- Reinheit:
- ≥95% by SDS-PAGE
- Lagerbedingungen:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Hersteller:
- East-Mab Biomedical
- Host:
- HEK293
- ABP:
- No Import Docs
- Formulierung:
- Lyophilized from a 0.22 um filtered solution containing 20mM Sodium acetate, 150mM NaCl, 5% Mannitol, 0.01%Tween 80, pH 5.5
- Format:
- Lyophilized powder
- Weitere Details:
- β-NGF (β-Nerve Growth Factor) is a neurotrophin belonging to the neurotrophic factor family. While structurally similar to other neurotrophins such as BDNF, NT-3, and NT-4/5, β-NGF specifically binds to the TrkA receptor (high affinity) and the p75NTR receptor (low affinity). In?in vitro?cultures, it primarily supports the survival, differentiation, and functional maintenance of specific neural populations, including sympathetic neurons, sensory neurons (e.g., dorsal root ganglion cells), and central cholinergic neurons (e.g., basal forebrain neurons). In downstream applications, β-NGF can be used in combination with stem cell cultures to induce the directed differentiation of neural precursor cells.
- Versandbedingungen:
- Blue Ice