Recombinant Human G-CSF

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£392.00

SKU:: Y06201
Zusätzliche Namen:: Granulocyte Colony-Stimulating Factor， CSF3
Anwendung:: Functional Assay
Molekulargewicht:: 18.7 kDa
Reinheit:: ≥95% by SDS-PAGE
Lagerbedingungen:: 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Hersteller:: East-Mab Biomedical
Host:: Hamster
ABP:: No Import Docs
Formulierung:: Lyophilized from a 0.22 um filtered solution containing PBS, 5% mannitol and 0.01% Tween 80, pH7.4
Format:: Lyophilized powder
Weitere Details:: G-CSF (Granulocyte Colony-Stimulating Factor), a member of the colony-stimulating factor family, is a single-chain glycoprotein with a molecular weight of approximately 19–22 kDa. As a crucial hematopoietic factor in cell culture, it specifically acts on myeloid hematopoietic cells—particularly the neutrophil lineage—to regulate their proliferation, differentiation, and function. By activating the G-CSF receptor (G-CSFR/CD114), it triggers signaling pathways such as JAK-STAT3, PI3K/Akt, and MAPK, thereby promoting the proliferation and differentiation of neutrophil precursor cells. Additionally, G-CSF enhances the function of mature neutrophils, inhibits their spontaneous apoptosis, and modulates inflammatory responses.