Y02701
Recombinant Human IL-15
Größe
£425.00
- SKU:
- Y02701
- Zusätzliche Namen:
- IL15, Interleukin-15, MGC9721
- Anwendung:
- Functional Assay
- Molekulargewicht:
- 12.7 kDa
- Reinheit:
- ≥95% by SDS-PAGE
- Lagerbedingungen:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Hersteller:
- East-Mab Biomedical
- Host:
- Hamster
- ABP:
- No Import Docs
- Formulierung:
- Lyophilized from a 0.22 um filtered solution containing PBS, 5% mannitol and 0.01% Tween 80, pH 7.4
- Format:
- Lyophilized powder
- Weitere Details:
- IL-15 (Interleukin-15) is a pleiotropic cytokine belonging to the common gamma-chain (γc) cytokine family. While structurally similar to IL-2, it exhibits distinct functional properties. It is primarily produced by antigen-presenting cells (such as dendritic cells and macrophages), epithelial cells, and fibroblasts, and acts through activation of the JAK-STAT signaling pathway, predominantly via JAK1/3 and STAT3/5. IL-15 is essential for the survival of memory CD8+ T cells and natural killer (NK) cells. In serum-free culture systems, it can substitute for serum by providing crucial survival signals, thereby promoting the persistence and proliferation of T and NK cells while enhancing NK cell cytotoxicity. As a key tool in tumor immunology, infectious immunity, and cell therapy research, IL-15 plays an especially indispensable role in experiments requiring long-term maintenance of immune cell activity.
- Versandbedingungen:
- Blue Ice