Y02201
Recombinant Human IL-4
Größe
£363.00
- SKU:
- Y02201
- Zusätzliche Namen:
- MGC79402，B-cell stimulatory factor 1，Lymphocyte stimulatory factor 1，IL4，Interleukin 4，B_cell Stimulatory Factor 1，B Cell Growth Factor 1，Binetrakin，Pitrakinra，BSF-1，Interleukin 4 Variant 2，BCGF-1，BCGF1，BSF1，Interleukin-4
- Anwendung:
- Functional Assay
- Molekulargewicht:
- 15.0 kDa
- Reinheit:
- ≥95% by SDS-PAGE
- Lagerbedingungen:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Hersteller:
- East-Mab Biomedical
- Host:
- Hamster
- ABP:
- No Import Docs
- Formulierung:
- Lyophilized from a 0.22 um filtered solution containing PBS, 5% mannitol and 0.01% Tween 80, pH 7.4
- Format:
- Lyophilized powder
- Weitere Details:
- IL-4 (Interleukin-4) is a cytokine primarily secreted by Th2 cells, mast cells, and basophils. It functions by binding to receptor complexes such as IL-4Rα/γc or IL-4Rα/IL-13Rα1, activating the JAK-STAT6 signaling pathway to regulate immune responses, cell proliferation, and differentiation. IL-4 modulates immune cell differentiation and function by promoting Th2 cell polarization and is commonly used in?in vitro?B cell culture systems. In organoid cultures, IL-4 acts synergistically with IL-13 to drive goblet cell differentiation and modulate the immune microenvironment in intestinal organoids. Additionally, IL-4 can suppress neuronal differentiation and promote the generation of astrocytes.
- Versandbedingungen:
- Blue Ice