G032
GMP Recombinant Human GM-CSF
Größe
£523.00
- SKU:
- G032
- Zusätzliche Namen:
- Granulocyte-Macrophage Colony-Stimulating Factor， CSF2
- Anwendung:
- Functional Assay
- Molekulargewicht:
- 14.5 kDa
- Reinheit:
- ≥95% by SDS-PAGE
- Lagerbedingungen:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Hersteller:
- East-Mab Biomedical
- Host:
- Hamster
- ABP:
- No Import Docs
- Formulierung:
- Lyophilized from a 0.22 um filtered solution containing PBS, 5% mannitol and 0.01% Tween 80, pH 7.4
- Format:
- Lyophilized powder
- Weitere Details:
- GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor), a member of the colony-stimulating factor (CSF) family, is a cytokine that regulates hematopoiesis and immune cell function. It is secreted by various cell types, including granulocytes, dendritic cells, T cells, and B cells, and primarily modulates cell proliferation, differentiation, survival, and function through the activation of specific signaling pathways such as JAK/STAT, MAPK, and PI3K.GM-CSF promotes the proliferation and differentiation of hematopoietic progenitor cells, and stimulates the lineage-specific differentiation and expansion of granulocytes (neutrophils, eosinophils) and macrophages. It also acts synergistically with cytokines such as IL-3 and SCF to enhance multi-lineage hematopoiesis.
- Versandbedingungen:
- Blue Ice