G028
GMP Recombinant Human BMP-2
Größe
£427.00
- SKU:
- G028
- Zusätzliche Namen:
- Bone Morphogenetic Protein 2，BMP-2，Bone morphogenetic protein 2A，BDA2，SSFSC，BMP-2A，BMP2A
- Anwendung:
- Functional Assay
- Molekulargewicht:
- 12.9 kDa
- Reinheit:
- ≥95% by SDS-PAGE
- Lagerbedingungen:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Hersteller:
- East-Mab Biomedical
- Host:
- E. coli
- ABP:
- No Import Docs
- Formulierung:
- Lyophilized from a 0.22 um filtered solution containing 0.1M Acetic acid, 5% Trehalose, pH 3.0
- Format:
- Lyophilized powder
- Weitere Details:
- BMP-2 (Bone Morphogenetic Protein 2), a member of the transforming growth factor-beta (TGF-β) superfamily, is synthesized in vivo as a precursor protein. Through proteolytic cleavage that removes the signal peptide and propeptide, it yields a mature peptide consisting of 114 amino acid residues. This mature peptide further forms homodimers or heterodimers via dimerization, thereby acquiring full biological activity. BMP-2 stimulates DNA synthesis and cell replication, promoting the directed differentiation of mesenchymal cells into osteoblasts. As a key factor inducing bone and cartilage formation in vivo, BMP-2 is expressed during limb growth, endochondral ossification, early fracture healing, and cartilage repair, playing a critical role in embryonic skeletal development and regenerative repair.
- Versandbedingungen:
- Blue Ice