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BNUM3799

Cytokeratin 6A (KRT6A) (Basal Cell Marker)(rKRT6A/2100), 1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:
BNUM3799
Zusätzliche Namen:
58kDa Cytokeratin; CK5; Cytokeratin-5; DDD1; Epidermolysis Bullosa Simplex 2 (EBS2); Keratin 5; Keratin; Type II Cytoskeletal 5; Keratin-5; KRT5; Type-II Cytoskeletal 5; Type-II keratin Kb5
Anwendung:
IHC-P
Konzentration:
1 mg/ml
Molekulargewicht:
58 kDa
Quelle:
Animal
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Biotium
Host:
Mouse
Reaktivitäten:
Human, Mouse
Buffer:
PBS, no BSA, no azide|PBS, no BSA, no sodium azide
Immunogen:
Recombinant full-length human Cytokeratin 6A (KRT6A) protein
Formulierung:
PBS, no BSA, no azide
Klon:
rKRT6A/2100
Uniprot:
P02538
Synonyme:
CK-6C;CK-6E;CK6A;CK6C;CK6D;cytokeratin 6A;cytokeratin 6C;cytokeratin 6D;Cytokeratin-6A;Cytokeratin-6D;K6A;K6C;K6D;keratin 6A, , type II;keratin 6A, type II;Keratin-6A;keratin, epidermal type II, K6A;keratin, type II cytoskeletal 6A;KRT6C;KRT6D;PC3;type-II keratin Kb6
Weitere Details:
This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Versandbedingungen:
Ambient