BNUM3795
GLUT-1 (Tumor Progression and Mesothelioma Marker)(rGLUT1/2476), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM3795
- Zusätzliche Namen:
- Erythrocyte/hepatoma glucose transporter; Glucose transporter type-1; GLUT1; GLUT1DS; GLUTB; GT1; GTG1; Gtg3; HepG2 glucose transporter; PED; RATGTG1; Solute carrier family 2; Solute carrier family 2; facilitated glucose transporter member 1 (SLC2A1)
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 55 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Recombinant fragment of human GLUT1 protein (around aa 203-305) (exact sequence is proprietary)
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- rGLUT1/2476
- Uniprot:
- P11166
- Synonyme:
- choreoathetosis/spasticity, episodic (paroxysmal choreoathetosis/spasticity);CSE;DYT17;DYT18;DYT9;EIG12;glucose transporter type 1, erythrocyte/brain;GLUT;GLUT-1;GLUT1;GLUT1DS;hepG2 glucose transporter;HTLVR;human T-cell leukemia virus (I and II) receptor;PED;receptor for HTLV-1 and HTLV-2;SDCHCN;solute carrier family 2 (facilitated glucose transporter), member 1;solute carrier family 2, facilitated glucose transporter member 1
- Weitere Details:
- Recognizes a protein of 55 kDa, which is identified as GLUT-1. Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1 is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung, bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiation of malignant mesothelioma (positive) from reactive mesothelium (negative). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient