Cathepsin D (Tumor Marker)(CTSD/3276), 1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:: BNUM3276
Zusätzliche Namen:: Cathepsin D; CTSD; Lysosomal aspartyl peptidase
Anwendung:: WB, IHC-P, IF
Konzentration:: 1 mg/ml
Molekulargewicht:: 46 kDa (Procathepsin D); 28 kDa (Cathepsin D)
Quelle:: Animal
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Biotium
Host:: Mouse
Reaktivitäten:: Human, Mouse
Buffer:: PBS, no BSA, no azide|PBS, no BSA, no sodium azide
Immunogen:: Recombinant fragment of human Cathepsin D protein (around aa 104-250) (exact sequence is proprietary)
Formulierung:: PBS, no BSA, no azide
Klon:: CTSD/3276
Uniprot:: P07339
Synonyme:: cathepsin D;ceroid-lipofuscinosis, neuronal 10;CLN10;CPSD;epididymis secretory sperm binding protein Li 130P;HEL-S-130P;lysosomal aspartyl peptidase;lysosomal aspartyl protease;protein ripply2
Weitere Details:: Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Versandbedingungen:: Ambient