BNUM2932
FCGRT / FcRn (IgG Transporter)(FCGRT/2932), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM2932
- Zusätzliche Namen:
- Fc fragment of IgG; receptor transporter; alpha; FCGRT; FCRN; alpha chain; IgG Fc fragment receptor transporter alpha chain; IgG Gc receptor; IgG receptor FcRn large subunit p51; Immunoglobulin receptor; intestinal; heavy chain; Neonatal Fc receptor
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 46 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Recombinant fragment of human FCGRT protein (around aa 24-215) (Exact sequence is proprietary)
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- FCGRT/2932
- Uniprot:
- P55899
- Synonyme:
- alpha-chain;Fc fragment of IgG, receptor, transporter, alpha;FCRN;FcRn alpha chain;heavy chain of the major histocompatibility complex class I-like Fc receptor;IgG Fc fragment receptor transporter alpha chain;IgG receptor FcRn large subunit p51;immunoglobulin receptor, intestinal, heavy chain;major histocompatibility complex class I-like Fc receptor;neonatal Fc receptor;neonatal Fc-receptor for Ig;transmembrane alpha chain of the neonatal receptor
- Weitere Details:
- This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient