BNUM2885
CD81 / TAPA-1 (C81/2885R), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM2885
- Zusätzliche Namen:
- CD81; Target of the antiproliferative antibody 1 (TAPA-1); Tetraspanin-28; Tspan-28
- Anwendung:
- Flow Cytometry, IHC-P
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 26 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rabbit, Rat
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- B-Cell line derived from a Burkitt lymphoma
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- C81/2885R
- Uniprot:
- P60033
- Synonyme:
- 26 kDa cell surface protein TAPA-1;cancer/testis antigen 40;CD81 antigen;CD81 antigen (target of antiproliferative antibody 1);CT40;CVID6;RNA polymerase II TBP-associated factor subunit Q;S5.7;TAF2Q;TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa;TAPA1;Target of the antiproliferative antibody 1;TATA box-binding protein-associated factor 50 kDa;TBP-associated factor, RNA polymerase II, Q;tetraspanin-28;transcription initiation factor TFIID 50 kDa subunit;transcription initiation factor TFIID subunit 7-like;tspan-28;TSPAN28
- Weitere Details:
- This antibody recognizes a protein of 26 kDa, identified as CD81 (Workshop VI; Code CD81.1). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspanin transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient