BNUM2880
Drebrin 1 (DBN1)(DBN1/2880), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM2880
- Zusätzliche Namen:
- Developmentally regulated brain protein; Drebrin 1; Drebrin; Drebrin E; Drebrin E2; Drebrin1; DrebrinE
- Anwendung:
- WB, IHC-P
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 120 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Recombinant fragment (aa 150-281) of human DBN1 protein (exact sequence is proprietary)
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- DBN1/2880
- Uniprot:
- Q16643
- Synonyme:
- D0S117E;developmentally-regulated brain protein;drebrin;drebrin A;drebrin E;drebrin E2
- Weitere Details:
- Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2); and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer's disease and Down syndrome. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient