BNUM2726
n-Myc (Neuroblastoma Marker)(NMYC-1), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM2726
- Zusätzliche Namen:
- Class E basic helix-loop-helix protein 37 (bHLHe37); MODED; N-myc proto-oncogene protein; Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene; ODED; pp65/67; v myc (avian) myelocytomatosis viral related oncogene neuroblastoma derived
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 67 kda
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Recombinant full-length human n-Myc protein.
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- NMYC-1
- Uniprot:
- P04198
- Synonyme:
- adhesion G protein-coupled receptor A2;bHLHe37;class E basic helix-loop-helix protein 37;G-protein coupled receptor 124;GPR124;MODED;N-myc;N-myc proto-oncogene protein;neuroblastoma MYC oncogene;neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene;NMYC;ODED;oncogene NMYC;TEM5;tumor endothelial marker 5;v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
- Weitere Details:
- The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein, designated Max. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient