Cytokeratin 13 (Non-Keratinized Squamous Epithelial Marker)(KRT13/2213), 1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:: BNUM2659
Zusätzliche Namen:: CK13; Cytokeratin-13; Keratin Type I Cytoskeletal 13; Keratin-13; KRT13; Type I Cytoskeletal 13; WSN2
Anwendung:: Flow Cytometry, IHC-P
Konzentration:: 1 mg/ml
Molekulargewicht:: 52 kDa
Quelle:: Animal
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Biotium
Host:: Mouse
Reaktivitäten:: Human, Mouse
Buffer:: PBS, no BSA, no azide|PBS, no BSA, no sodium azide
Immunogen:: Recombinant full-length human KRT13 protein
Formulierung:: PBS, no BSA, no azide
Klon:: KRT13/2213
Uniprot:: P13646
Synonyme:: CK-13;CK13;cytokeratin 13;Cytokeratin-13;K13;keratin 13, type I;Keratin-13;keratin, type I cytoskeletal 13;WSN2
Weitere Details:: Cytokeratin 13 (KRT13) is the major acidic keratin, which together with KRT4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia including tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder, which predominantly affects non-cornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. KRT13 has been used as a marker for non-keratinized squamous epithelium. It is also expressed in various squamous metaplasia, but it is down regulated in squamous dysplasia and squamous carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Versandbedingungen:: Ambient