BNUM2652
B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM2652
- Zusätzliche Namen:
- B7-H4; B7H4; B7X; B7 family member; H4; B7 homolog 4; B7 superfamily member 1; B7S1; B7 family member H4
- Anwendung:
- Flow Cytometry, IHC-P, IF
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 35 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Rabbit
- Reaktivitäten:
- Human, Rabbit
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Recombinant human B7-H4 protein fragment (exact sequence is proprietary)
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- B7H4/2652R
- Uniprot:
- Q7Z7D3
- Synonyme:
- B7 family member, H4;B7 homolog 4;B7 superfamily member 1;B7-H4;B7h.5;B7H4;B7S1;B7X;immune costimulatory protein B7-H4;PRO1291;Protein B7S1;T cell costimulatory molecule B7x;T-cell costimulatory molecule B7x;V-set domain-containing T-cell activation inhibitor 1;VCTN1
- Weitere Details:
- B7-H4 (B7-homolog 4), belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells, B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies, including ovarian and breast cancer, as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that, similar to Mucin 16 (CA-125), B7-H4 may be a useful biomarker for the early detection of ovarian cancer.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient