Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), 1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:: BNUM2651
Zusätzliche Namen:: Cytokine Synthesis Inhibitory Factor (CSIF); GVHDS; IL-10; IL10; IL10A; Interleukin-10; T-cell Growth Inhibitory Factor (TGIF)
Anwendung:: IHC-P
Konzentration:: 1 mg/ml
Molekulargewicht:: 20 kDa (Monomer); 37 kDa (Dimer)
Quelle:: Animal
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Biotium
Host:: Rabbit
Reaktivitäten:: Human, Rabbit
Buffer:: PBS, no BSA, no azide|PBS, no BSA, no sodium azide
Immunogen:: Recombinant full-length human Interleukin 10 (IL10) protein
Formulierung:: PBS, no BSA, no azide
Klon:: IL10/2651R
Uniprot:: P22301
Synonyme:: CSIF;cytokine synthesis inhibitory factor;GVHDS;IL-10;IL10A;interleukin-10;T-cell growth inhibitory factor;TGIF
Weitere Details:: Interleukin 10 (IL10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immuno-regulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immuno-regulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Versandbedingungen:: Ambient