NKX2.8(NKX28/2548), 1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:: BNUM2548
Zusätzliche Namen:: Homeobox protein NK 2 homolog H; Homeobox protein NK-2 homolog H; Homeobox protein Nkx 2.8; Homeobox protein Nkx-2.8; NK 2 homolog 8; NK 2 homolog H; NK2 homeobox 8; NK2 transcription factor related; locus 8; Nkx2 9; Nkx2-8; NKX2.8; NKX28_HUMAN; NKX2G; NKX2H; OTTHUMP00000027959
Anwendung:: WB
Konzentration:: 1 mg/ml
Molekulargewicht:: 26 kDa
Quelle:: Animal
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Biotium
Host:: Mouse
Reaktivitäten:: Human, Mouse
Buffer:: PBS, no BSA, no azide|PBS, no BSA, no sodium azide
Immunogen:: Human recombinant NKX2.8 protein fragment (around aa 10-123) (exact sequence is proprietary)
Formulierung:: PBS, no BSA, no azide
Klon:: NKX28/2548
Uniprot:: O15522
Synonyme:: homeobox protein NK-2 homolog H;homeobox protein Nkx-2.8;NK-2 homolog 8;NK-2 homolog H;NK2 transcription factor related, locus 8;Nkx2-9;NKX2.8;NKX2H
Weitere Details:: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Versandbedingungen:: Ambient